Sensitivity Analysis and Risk Incorporation in Capital Budgeting

Questions
Prepare a PowerPoint presentation on this topic. Include the following:
Title slide . 
5-7 content slides (Not including Title and Reference Slide) explaining the qualitative and quantitative steps necessary in conducting a Sensitivity Analysis. How can a project’s risk be incorporated into a Capital Budgeting analysis? Use concise bullet points on the slide and the Speaker Notes section to add details for each slide (this becomes your video “speech”).
 Minimum of 2 References.
A+ work required 
Must be plagiarism free. 

Answer
1. Introduction
In either case the evaluation is easier said than done. High risk investment opportunities are often rejected because it is difficult to quantify the risk and many different probability of success weighted cash flows could yield an unsatisfactory expected return. This is where risk incorporation in capital budgeting can provide a simple yet powerful tool to quantify risk and improve investment decisions.
It is impossible however, to predict the cash flows from investment project with perfect accuracy. Some factors are relatively certain to be correct in their expectation such as a firm’s term structure on their outstanding debt, the sensitivity of these cash flows given a particular interest rate could be measured quite precisely. A sensitivity analysis in this situation would involve a simulation to estimate the change interest rates given a time. On the other hand, if a firm is investing to launch a new product or service and have very little information about the market demand, the cash flows and expected rate of return from the opportunity are highly uncertain.
In recent years, sophisticated techniques for evaluating investment opportunities have been developed in the areas of sensitivity analysis and risk incorporation. Capital budgeting is by now a well-developed and critical organizational planning process field that helps to evaluate and select investment projects that will yield long run profits and/or cash flows that surpass a company’s cost of capital. At the heart of it, capital budgeting is a search for the rate of return, r, that will maximize the market value of a firm’s common stock. This involves analytical processes ranging from finding cost of debt or equity, to adjusting for risk in the cash flows that are being estimated from a particular investment opportunity. With the growth of computing power and information technology it has become more feasible intuitively and statistically evaluate a particular investment opportunity, incorporating modern portfolio theory and an overall trend toward higher risk investments. It is clear the importance of evaluating an investment’s risk and or return.
1.1 Purpose of the Presentation
Capital budgeting decisions are among the firm’s most critical strategic decisions because of their long term, high cost, and difficult-to-reverse nature. These characteristics make capital budgeting decisions the most likely to be erroneous of all decisions, thereby creating a significant business risk. It is for these reasons that the purpose of this presentation is to stress the importance of utilizing sensitivity analysis and risk incorporation when making capital budgeting decisions. This paper will first define and outline the importance of sensitivity analysis and risk incorporation when making capital budgeting decisions. Simulation analysis is an extension of these methods and is more complex and computationally demanding. Simulation analysis has been proven to be useful in the evaluation of projects and also is an effective method to incorporate risk. Simulation uses a model that describes the probability distributions of various input variables and generates a probability distribution for the NPV of the project. By creating a probability distribution of expected NPV, management can see the distribution risk of a project. Simulation can be very beneficial in risk assessment. Through these various methods, there are many ways to incorporate risk in the evaluation of a capital budgeting decision. The paper will also examine several different aspects of risk and how it can be incorporated into a project to increase the accuracy of the net present value. By doing this, we hope to inform financial managers of the benefits of using these methods and convince them to utilize them when making capital budgeting decisions. Following the examination of these methods, the paper will present an example that employs each method in a comprehensive manner so that the reader may better understand how to apply them. Finally, the paper will conclude with a summary of the methods and findings.
1.2 Importance of Sensitivity Analysis and Risk Incorporation
Sensitivity analysis is the effect of change in a dependent variable when an independent variable is changed. Such analysis is of crucial importance in taking investment decisions, especially in capital budgeting, because of the long-term and irreversible nature of the decisions. There is no point in taking a decision now that something cannot be done in the future, unless one can foresee that future conditions will make the thing more valuable to do then. Then postponing the decision is an immediate choice. If managers knew precisely the future economic conditions in terms of the variables such as costs of material, inflation rate, labor, etc., they could plug these into their capital budgeting model and then make an exact decision. Unfortunately, nobody knows the future and assumptions concerning the future are based on forecasting of the economic variables which are always subject to error. Now comes the question of what to do given an error in the forecast. Generally, the future variable is assumed to be more or less known and a range of values is assigned to it. Here, in between the decision made now and the variable, there exists an optimal strategy to reach the decision and the variable can be used as an independent variable. Given that capital budgeting decisions are usually taken over a period of time with the outlay of money at various times, the decision variable may be an outlay which can be seen as an investment at the different times and the variable its rate of return. Now a rate of return can be a very deciding factor to continue or abandon a certain investment and probability in the case of abandonment is that the investment is not worthwhile. To relate this to an earlier example, if an optimal strategy for a series of decisions exists and the probable rate of return on the investment is known, then a decision can be mapped to the rate of return and investment, and it is possible to simulate a series of decisions using the decision variables and stopping the simulation at a time if the investment is abandoned. Simulation techniques are very flexible and complicated ones can be used to directly replicate the real system and answer what would happen if a change were made.
2. Qualitative Steps in Conducting a Sensitivity Analysis
2.1 Identifying Key Variables
2.2 Determining the Range of Values
2.3 Assessing the Impact on Outcomes
3. Quantitative Steps in Conducting a Sensitivity Analysis
3.1 Assigning Probability Distributions to Variables
3.2 Performing Monte Carlo Simulations
3.3 Analyzing the Results
4. Incorporating Project Risk into Capital Budgeting
4.1 Evaluating Risk Factors
4.2 Adjusting Cash Flows and Discount Rates
4.3 Assessing the Impact on Project Viability
5. References

Human Augmentation and the Blurring Lines: The Ethical Development and Use of Human Augmentation Technologies

QUESTION
Human Augmentation and the Blurring Lines: Technological advancements like brain-computer interfaces and wearable exoskeletons are pushing the boundaries of human capabilities. How can human informatics guide the ethical development and use of human augmentation technologies, ensuring they enhance rather than redefine what it means to be human?

ANSWER
1. Introduction
First, while only a few of these technologies are in use or close to implementation today, the timescale between development and implementation may not be adequate for thorough examination of ethical issues before it is too late to affect how the technology will be used. Policy regarding the use of enhancement technologies has tended to lag behind scientific and technological progress, enforcing a reactive rather than proactive approach to ethical evaluation. Second, ethical debate and policy regarding human enhancement technologies has been quite fragmented and not born much fruit in terms of policy and guidelines for scientists and developers of these technologies. This form of corporate social responsibility is crucial for maintaining a proactive approach to ethical evaluation. Allhoff has proposed that the best means to address issues in the long term is to shape the nature and direction of technological change, steering it towards more desirable ends, and enhancing oversight, and looking to its social implications from the outset (Allhoff 2010). Thus it is necessary to examine the ethical issues surrounding human augmentation technologies in a broad and inclusive manner and make it a priority to integrate policy and guidelines for scientists into the fabric of these technologies’ development.
Human augmentation technologies, which have the potential to bring about radical improvements to the human condition, are increasingly evoking public and academic debate. Labeled as the most important social and ethical issue of the twenty-first century (Allhoff et al. 2009), the development and use of human enhancement technologies has spurred a plethora of argument from ethicists, scientists, policymakers, and the general public. People are concerned about how it will affect what it means to be human, the distribution of the technology, and the potential for new forms of unequal social pressure to enhance. Others are hopeful about the possibility of new treatments for currently incurable diseases and conditions, as well as providing a means to improve the intellectual, physical, and psychological capacity of humans. The rapid development of these technologies presents two main challenges for the gradual process of ethical evaluation and policy development.
1.1. Background of Human Augmentation Technologies
The goal of human augmentation, to use medical technology in order to improve physical performance or even overcome disabilities, has existed for thousands of years. The development of new medical techniques and the convergence of these techniques with computer technology, new materials sciences and nanotechnology, will have far-reaching effects on the lives of every human being, as well as on the global ecosystem. To discuss the future of human augmentation, it is important to understand the historical precedents. The past three decades have seen incredible advances in medical technology. Joint replacements, dental reconstruction, organ transplants, cosmetic surgery, and the alleviation of mental illnesses through drug therapy are now commonplace in the developed world. These developments have been driven by a number of factors, including the desire of individuals to lead more fulfilling lives, an aging global population, and the economic and social benefits that improved health provides. The development of human augmentation technologies has been largely driven by the needs and capabilities of the medical industry. It is, however, the commercial potential of such technologies, particularly in an age of growing economic inequality and a global ‘knowledge economy’, that is likely to be the ultimate driving force behind the future development and convergence of these technologies. The medical industry has traditionally been conservative and slow to implement radical new procedures. Often new technologies were tested and perfected on relatively small and specific patient groups. As these technologies became more refined and costs were reduced, wider ranges of patients were treated. Many possibly beneficial medical technologies have had limited success as they were superseded by new technologies or were not seen as economically viable by the industry. This has resulted in an increasing proportion of the world’s population being left behind by the rapid pace of change in the medical industry.
1.2. Importance of Ethical Considerations
There are ethical issues associated with the development and offering of human augmentation technologies. The implications of the effectiveness and pervasiveness of those technologies will have wide-ranging effects on society. In the short term, human enhancement technologies might exacerbate social inequalities and create a two-tier society, further the gap between the haves and the have-nots. Because many enhancement technologies will initially be costly, they may be deployed first and most aggressively by those who can afford them, thus widening the gap and ultimately solidifying the advantages that already accrue to the more affluent members of society. This might, in turn, lead the wealthy to distance themselves from the less fortunate, leading to an erosion of empathy and the virtual marginalization of the unenhanced. This potential future is dystopic, and the transparency and openness to scrutiny of the later on possible more drastic changes to our species, whether by genetic enhancement or cybernetic technologies, would reduce the possibility that we could slide into such a state unwittingly. If a given alteration to humanity is deemed so undesirable that it should be prevented at all costs, knowing what constitutes that kind of alteration and having an open forum to decide its nature and the steps to prevent it is critical. Human augmentation technologies pose subtle changes to human nature, and it is important that we make decisions about these technologies intentionally, rather than let them determine the future of humanity by happenstance.
2. Human Informatics: Guiding the Ethical Development
2.1. Definition and Scope of Human Informatics
2.2. Role of Human Informatics in Technology Development
2.3. Ethical Principles in Human Informatics
3. Human Augmentation Technologies: Enhancing Human Capabilities
3.1. Brain-Computer Interfaces: Expanding Cognitive Abilities
3.2. Wearable Exoskeletons: Enhancing Physical Performance
3.3. Prosthetic Limbs: Restoring Functionality
4. Ethical Considerations in Human Augmentation
4.1. Autonomy and Informed Consent
4.2. Privacy and Data Security
4.3. Equality and Accessibility
5. Ensuring Ethical Use of Human Augmentation Technologies
5.1. Regulatory Frameworks and Policies
5.2. Ethical Design and Development Guidelines
5.3. Education and Awareness
6. Implications of Human Augmentation on Society
6.1. Impact on Employment and Workforce
6.2. Social and Cultural Norms
6.3. Psychological and Emotional Effects
7. Future Perspectives and Challenges
7.1. Emerging Technologies in Human Augmentation
7.2. Balancing Innovation and Ethical Considerations
7.3. Addressing Potential Risks and Unintended Consequences
8. Conclusion

Improving Client-Centered Care Initiatives in Advanced Practice Nursing

questions
General Instructions
Advanced practice nurses apply continuous quality improvement (CQI) processes to improve client-centered outcomes. Select one of the following client-centered care initiatives that you would like to improve in your practice area: client clinical outcomes, client satisfaction, care coordination during care transitions, or specialty consultations for clients.   
Include the following sections:
1. Application?of?Course?Knowledge: Answer all questions/criteria with explanations and detail.
·   
a.  Identify the selected client-centered care initiative and describe its application to your future practice.  
b.  Select one CQI framework that can be applied to the selected initiative. Explain each step of the framework. 
c.  Describe how the framework can improve client-centered care for the selected initiative. 
d.  Describe how you would involve interprofessional team members in the CQI process.  

Answer
1. Introduction
Through the tumultuous climate of the United States health care environment, acute care has emerged as a focus of treatment. Advanced practice nurses (APNs) are progressively introduced into the system equipped with potent skills, sheer competence, and autonomy to provide excellence of service and care for the patients. APNs do not merely attend to the patients’ health illnesses and disease conditions but also investigate and implement plans for the prevention of illness and the promotion of healthier living. They strive to bridge the gap in quality of care available between conventional primary care and specialist services by creating a comprehensive care delivery system centered on the patients. Since the 1960s, patient-centered advanced practice nursing care has been the vision and hallmark of nursing practice today. APNs use their metaparadigm knowledge in application to care for patients and establish comfort and trust within the healer/healee relationship. Despite being trained in pathophysiology and the extant medical model, advanced practice nurses awaken each day with knowledge that the patient is a unique, dynamic individual, the locus of control for the nurse’s actions. Subsequently, plans to improve upon this type of care were investigated through the review of an article titled “Improving Client-Centered Care Initiatives in Advanced Practice Nursing”. This article examines 4 research-informed initiatives that have the potential to improve care outcomes and systems for APN care from the US and globally. That two respondents sought out to examine the advancement and outcomes of care systems truly indicates the spirit of APN initiatives for the betterment of society. Methodology involved examination of care systems in 2 different developed countries, comparing results to determine best efficacious methods and to incorporate ideas of quality care leadership into present and future initiatives. These initiatives are parallel to the moral and inner directive of all APNs and directly reflect how APNs would seek to improve care provided to themselves as clients. As a profession largely consisting of second career adults who are intrinsically motivated and often times highly advanced academically, APNs themselves are a unique client group and an often overlooked one at that. An aggregate systems theory serves to build frameworks and initiatives to improve care delivery for all types of clients, including the providers themselves. With a solid foundation of theoretical frameworks and research infusion, these initiatives serve to improve health, augment nurse and system outcomes, and change the face of nursing as we now know it. In an effort to align with the vision of a global society, the methods in which this research was initiated are undoubtedly impressive. An era of increased nursing professional involvement and participation in national and international policy has seen the development of nursing research and quality care initiatives based on evidence-based practice and utilizing comparative methods. This research is an exemplar and has the potential to shape future care systems both locally and abroad.
1.1. Background and Context
APNs practice has grown significantly over the years. This growth has been stimulated by the continuing shortage of physicians, the growth of managed care, and a clear and consistent, well-documented record of safe and effective practice. Managed care has evolved through models such as health maintenance organizations (HMOs), preferred provider organizations (PPOs), and point of service (POS) plans. APNs are recognized for their ability to provide cost-effective care and are employed in a variety of settings to assist in cost saving measures. As health care reform is once again on the forefront of American politics, it is evident that APNs currently practicing or those that will practice in the future, must be prepared to navigate through and affect change within the complex health care system. This poses a profound challenge to those APNs who have been educated and honed their practice in a context largely removed from today’s health care system. It is a stimulation to define practice and move it closer to the ideals of APN and improve patient outcomes.
The first graduate program for advanced practice nursing (APN) (nurse practitioner, nurse midwifery, nurse anesthesia, clinical nurse specialist) was developed by the University of Colorado in 1965 (Dimeo, 2008). The program was established to prepare nurses in the primary care role to meet the needs of the medically underserved. At that time, the IOM had defined primary care as the provision of integrated, accessible health care services by clinicians who are accountable for addressing a large majority of personal health care needs, developing a sustained partnership with patients, and practicing in the context of family and community (IOM, 1996). Primary care should be the first element of a continuing healthcare process and the system of family and community should be a partnership between the patient and the provider working to promote health and prevent disease. Primary care provider should be the coordinator for any specialty care or hospitalizations and the patient should be provided care that is cost-efficient and meets the needs of the patient. Today, APNs are providing primary care in outpatient and community-based settings, and have come closer to achieving these goals of primary care. They are educated to provide a full range of services to meet the needs of their patients.
1.2. Purpose of the Work
This comprehensive work was generated to improve “client” people-centered treatment initiatives within the context of advanced practice nursing. Towards that goal, the methods to improve client-centered treatment within a current APN practice were investigated. These methods are supported through amendments to the current system of care, use of direct and indirect clinical interventions, as well as involving clients in health education and promotion. The foundation for this work comes from research stating that Dimatatis et al. (1999) found that clients diagnosed with chronic conditions tend to be more compliant and satisfied with their treatment when they perceive the medical system to be more aligned with their own values and treatment preferences. This study serves to combine practice wisdom with scientific evidence to these ends.
2. Application of Course Knowledge
2.1. Selected Client-Centered Care Initiative
2.2. Importance of the Initiative in Future Practice
3. Continuous Quality Improvement (CQI) Framework
3.1. Selection of CQI Framework
3.2. Explanation of Each Step in the Framework
4. Improving Client-Centered Care
4.1. Enhancing Client Clinical Outcomes
4.1.1. Point 1: Implementing Evidence-Based Practices
4.1.2. Point 2: Monitoring and Evaluating Treatment Plans
4.2. Increasing Client Satisfaction
4.2.1. Point 1: Enhancing Communication and Education
4.2.2. Point 2: Addressing Client Preferences and Needs
4.2.3. Point 3: Ensuring Timely and Responsive Care
4.3. Coordinating Care Transitions
4.3.1. Point 1: Establishing Effective Communication Channels
4.3.2. Point 2: Collaborating with Interprofessional Teams
4.3.3. Point 3: Implementing Care Transition Protocols
4.4. Facilitating Specialty Consultations
4.4.1. Point 1: Identifying Appropriate Referral Criteria
4.4.2. Point 2: Streamlining Consultation Processes
4.4.3. Point 3: Ensuring Seamless Integration of Specialty Care
5. Involving Interprofessional Team Members
5.1. Importance of Interprofessional Collaboration in CQI
5.2. Roles and Responsibilities of Team Members
5.3. Strategies for Effective Team Engagement
6. Conclusion

Infectious Diseases and Viruses

question

1- What does the term ‘germs’ usually refer to? 
2- What do all germs have in common? 
3- Define the term ‘modes of transmission’ and give an example. 
4- What is a major disadvantage to a virus, if it replicates too much, too quickly? 
5- If there’s too little of a virus, what is a disadvantage (to the virus) if you don’t experience any symptoms? 
6- List the characteristics of a successful virus. 
7- What does the trade-off hypothesis predict for rhinovirus? 
8- Why does the malaria virus do not require a mobile host? 
9- What can we do to minimize the harmfulness of infectious diseases?
Answer
1. Introduction to Germs
It is highly improbable that a person of adult age could have lived in a household in a semi-sterile environment or worked in an industry which has top-notch cleanliness. Even though people may not be able to visualize germs, mold, and other biohazardous agents, they are always aware of the precautionary methods and practices which aim to bound these unwanted visitors from the realm of clean indoor living or working space. Whether it is teaching children to wash their hands before meals or, in some cases, after, using antibacterial soaps and lotions or spraying down kitchen and bathroom surfaces with chemical disinfectants, people are fighting a seemingly never-ending battle to rid our living spaces of germs. With the recent outbreak of diseases such as SARS, H1N1 virus, and increasingly high numbers of food poisoning cases, it is becoming more important to have a comprehensive understanding of what a germ is and its role as a causative agent of disease. The infamous people of the pre-germ theory era conducted acts such as opening the abdominal cavities of the deceased using bare hands and with no more protection than a blood-stained apron, to cutting the utensils and items used in surgery and not washing them, have an extreme appreciation of what a germ is and the effect of its presence.
1.1. Definition of ‘Germs’
Enough to be seen with the unaided eye. We will call these invisible living beings germs. This definition includes bacteria, fungi, various parasites, and viruses. Germs are limited by being too small to see without a microscope. Bacteria are made up of only one cell, but they are all around us and on us and even in us. Fungi are multi-celled plant-like organisms (such as mushrooms) that also include single-celled species (such as yeasts) and are also found everywhere, often in the form of mold. Many parasites are large enough to be seen. For example, worms are parasites. But this definition includes some parasites that are too small to be seen, such as the ones that cause malaria, which are single-celled organisms called plasmodia. The only exception to this definition is viruses, which are smaller than the smallest cells. While not all viruses are germs in the usual sense, this definition includes them because they are the cause of very many infectious diseases, and they are the only living organisms whose natural state is to exist only inside cells. Viruses are difficult to classify as microorganisms, as they are not truly alive. But they are invariably disease-causing, and this is the key attribute to germs in the context of infectious diseases.
1.2. Common Types of Germs
Viruses are small capsules containing genetic material. They are parasites in other organisms, including people, causing a range of diseases. The common cold, influenza, and warts are all caused by viruses. A virus can only reproduce within the cells of the host it invades, as it reprograms the cell to produce the components necessary for its replication. In most cases, viruses damage or kill the cells, then lie dormant for a period of time before reappearing, causing extensive long-term damage. The cell damage and the immune system’s response to the infection cause the symptoms of viral diseases. The immune system usually eliminates the virus from the body, and the infection is resolved. However, in some cases, such as HIV and Epstein-Barr, the virus evades the immune system, and the infection becomes chronic. Antiviral drugs are selective for viruses in that they can impair virus replication without harming normal host cells. However, due to the difficulty in targeting the viruses and not the host cells, these drugs often have limited effectiveness.
Bacteria are tiny, one-celled creatures that get nutrients from their environments in order to live. In some cases, that environment is a human body. Some bacteria actually cause disease, while others are helpful and even necessary to good health. Lactobacillus bulgaricus, for example, lives in the intestines and helps digest food. The bacteria in yogurt is probably the most known example of Lactobacillus bulgaricus. A few bacteria, such as the mycobacteria, are not harmful in general but can cause disease in a person whose immune system is not working properly. For example, Mycobacterium avium-intracellulare can cause a serious disease. More information is available on this in the Immune System and Disorders Article. Bacteria can cause many types of infections varying in severity. Infections occur as the bacteria try to make the body an environment more suitable for them to live in, reproducing and furthering their harmful effects. In infecting the body, bacteria can damage cells or interfere with cell function. They may release toxins which can damage the whole body. This then becomes a generalized infection. Symptoms of infection can vary but often include inflammation, fever, and fatigue. Bacterial infections are usually treated with antibiotics, which are chemicals designed to destroy or weaken the bacteria. High-level or broad-spectrum antibiotics are effective against a wide range of bacteria, and low-level antibiotics are often used to keep certain bacteria at bay. Amoxicillin use for prevention of Urinary Tract infections is an example of this. Antibiotics seldom have no effect on symptoms since they may cause removal of the bacteria and toxins that have caused damage or particular symptoms. Antibiotics have had a major impact on the length and severity of bacterial infections and on general public health.
Many people are familiar with the term “germs” referring to the tiny, microscopic organisms that cause disease. Until the invention of the microscope, scientists did not realize that germs existed, and people thought that disease was caused by bad air, spirits, a punishment from a god or simply fate. However, we now know that 4 main types of germs cause infectious disease. These are bacteria, viruses, fungi, and protozoa. Each of these types has its own structure, behaviors, and effects on the human body.
1.3. Role of Germs in Infectious Diseases
The organisms explained in the previous sections cause disease because they circle the primary location of the infectious organism that multiplies and causes trouble for the host. Now, disease is essentially a battle between two invasive organisms: the germ and the human. Disease occurs when the germ is successful in the battle with the human. The severity of that battle is what determines the severity of the disease. They are successful at causing disease when there is a portal of entry available to them. They are able to attach to the cells, grow and multiply, remain undetected by the immune system, and then cause damage to the cells and tissues. Germs in general are very adaptable, and that is why they are very successful at causing disease. Unfortunately, not all new strategies for the germ are successful in overcoming the immune system and resulting in disease. An example of this is the common cold, where there are over 200 different viruses that cause cold-like symptoms. Usually, it is insufficient in overcoming the immune system to cause serious illness, and symptoms of disease are only mild. This is known as colonization of the host, and many common diseases are simply a result of the germ trying to colonize and the battle between the germ and human causing only mild disease.
2. Common Characteristics of Germs
2.1. Key Features of Germs
2.2. Similarities Among Different Types of Germs
2.3. Importance of Understanding Germs’ Commonalities
3. Modes of Transmission
3.1. Definition of ‘Modes of Transmission’
3.2. Examples of Different Modes of Transmission
3.3. Significance of Understanding Transmission Methods
4. Viral Replication and Disadvantages
4.1. Consequences of Excessive Virus Replication
4.2. Negative Impact of Rapid Virus Replication
4.3. Effects of Overabundance on Virus Survival
5. Implications of Low Virus Levels
5.1. Disadvantages of Insufficient Virus Presence
5.2. Lack of Symptoms and Virus Survival
5.3. Importance of Detecting Low Virus Levels
6. Characteristics of Successful Viruses
6.1. Traits of Highly Effective Viruses
6.2. Factors Contributing to Virus Success
6.3. Understanding Successful Virus Traits
7. Trade-Off Hypothesis for Rhinovirus
7.1. Predictions Based on the Trade-Off Hypothesis
7.2. Implications for Rhinovirus Survival
7.3. Analyzing the Trade-Off Hypothesis in Rhinovirus
8. Malaria Virus and Host Mobility
8.1. Factors Influencing Malaria Virus Transmission
8.2. Lack of Mobile Host Requirement in Malaria Virus
8.3. Understanding Malaria Virus Transmission Mechanisms
9. Minimizing Harmfulness of Infectious Diseases
9.1. Strategies for Controlling Infectious Diseases
9.2. Importance of Preventive Measures
9.3. Promoting Public Health Initiatives

Influence of Culture on Cross-Border M&A Activity

QUESTION
How does culture influence cross-border M&A activity? Illustrate this relationship using examples, either real (even anecdotal if you have any) or conceptual. How do similar and dissimilar cultures affect pre- and post-merger performance?
ANSWER
1. Introduction
Organizational culture will not be the main focus of the study since its impact on M&A activity has been studied in depth in management literature. A holistic case study of the merger between the German company Daimler-Benz and US firm Chrysler will be used since this is considered a classic example of clash of national cultures. The inductive methodology used in the Daimler-Chrysler case will be initially used in the attempt to separate national culture from organizational culture and study its direct impact on M&A activity. Any findings and conclusions drawn from this case study will be initially tested against any theory provided in management literature. The aim in the end is to possibly come up with a new model explaining the impact of culture on M&A activity, which will be a useful framework for managers in the future.
In this research paper, the focus will be on studying the importance of culture in M&A activity. The objective of the paper is to separate the impact of national culture from organizational culture on M&A activity. The distinction between the two is important since national culture is considered an unmanageable force a firm encounters when it operates in a foreign environment, while organizational culture is a manageable force the firm can manipulate in order to coordinate and integrate activities when working with a potential partner.
Globalization has led to ever-increasing business activity across national borders. This has fueled the pace of cross-border mergers and acquisitions (M&A) in today’s global economy. Culture has been identified as a critical factor which has a significant impact on the outcome of international business activity. Cross-border M&A is an activity that takes place when a company from one country merges or takes over the assets of a company in another country.
1.1 Importance of Culture in Cross-Border M&A
Despite the prevalence of literature regarding the role culture plays in business, in particular cross-border mergers and acquisitions (M&A), it remains a relatively unexplored and underestimated factor in comparison to other theoretical lenses such as synergy or agency theory. It is widely recognized that national cultural differences are to be found in the differing thoughts, actions, assumptions, and a range of behavioral and material artifacts (Hofstede, 2002); all of which are key components of a society. That said, the fragmented and multidisciplinary nature of cultural theory development to date, it has yet to be fully integrated into M&A research and practice. However, there are various instances within the literature that infer assumptions to the effects of culture on M&A. For example, it is often cited as a reason for failure (Cartwright and Cooper, 1992), a costly barrier to be overcome during post-merger integration (Haspeslagh and Jemison, 1991), or a factor that should be included in the pre-acquisition screening process (Prahalad and Doz, 1987). While these examples bestow importance, it is not sufficient evidence to unequivocally prove it as a critical factor in M&A, and to date there is no defined framework or model that seeks to understand culture with respect to an entire M&A process. This is not to say cultural impact is always negative; a recent study by Stahl and Voigt (2008) identified that high cultural differences between two companies could lead to a lesser likelihood of bidder overpayment in an acquisition deal. However, the context of this result was within financial terms rather than the long-term integration process, and as aforementioned, this is not a widely explored area. With this considered, on the basis that culture is a central aspect of national identity, it can be viewed as a key and relevant aspect to any process involving two differing nations or organizations. This does not necessarily imply that any M&A between two differing national organizations will be heavily influenced by culture, for culture is a very broad and subjective concept, and there are varying levels of cross-border M&A; hence, the theory suggests that cultural impact will vary depending on the circumstance.
1.2 Objectives of the Study
The primary goal of this project is trying to figure out the impact of national and organisational culture on cross-border mergers and acquisitions, in the hope that better understanding of the influence of culture can help in avoiding some of the obvious pitfalls, and lead to successful integration which is the ultimate mark of a successful M&A activity. As this is an exploratory study, no hypothesis is put forward as it seeks to find new insights and information in the hope of forming a new theory. This has led to much of the research being in a more qualitative manner, although many questions do lend themselves to quantitative analysis. Measures of national culture provide a good base to look at the cultural issues, and matched-pair studies of companies involved in M&A activity can give good indications of the influence of culture on M&A and what actually occurs during the process. By looking at the level and nature of the increased M&A activity in the last 15 years, from the standpoints of both acquiring company and target firms, insights can be gained as to why the increase in M&A activity has led to mixed results, and how culture may be a key factor regarding this. Being an exploratory study, no specific culture dimension or issue is singled out, rather it looks at broad overall influence that culture may have at the national and organisational levels. A literature review is done on the failures and success stories of M&A activity, and there have been many case studies that offer comparisons such as two companies of different nationalities, one which has succeeded in M&A activity and one which has not. This provides much insightful data for the matched-pair studies and goes towards meeting the goals of this research.
1.3 Methodology
Another belief is that the culture of a society can be described by the values and norms present (Tayeb, 2000). Although it is possible to measure culture directly with various means, indirect measurement is probably the most effective, possibly using a society’s political or legal systems as a function of the culture it represents. Due to the breadth of values, norms, and the multi-level nature of culture, measuring the exact effects of culture on M&A activity is problematic and has only been extensively attempted by the very biggest firms in simulated training exercises. This encompasses a number of variables that would be best done by multiple means and at various levels, to provide a comprehensive understanding of the various issues involved. This too is evident throughout the research, as nearly all the micro-level events that created problems during M&A could always be related back to a difference of values or norms.
The research’s underpinning philosophy is the belief that culture affects behavior. This belief was supported by Yalcintas (1981), Guy and Beddow (1983), and Seth (1986). Yalcintas suggested that M&As were of an international nature and therefore present many problems in terms of differences in national policies, mentalities, and ways of doing business. Guy and Beddow and Seth also suggested that the variables of nationality and culture were of major import in M&A activity and provide one of the better frameworks within which to understand M&A behavior (Guy and Beddow, 1983; Seth, 1986 cited in Cartwright and Cooper, 1993). This belief was held throughout the EFA and case study and remained evident in the various responses received during the research, and some of the contradictions and practical problems that were found; each of which was possible to explain by cross-cultural differences. If we consider Schneider and Barsoux’s argument that cultural variation causes different mental programming, which creates ambiguity in cross-cultural encounters (Schneider and Barsoux, 1997), i.e. different behavioral patterns and an expectancy of behavior between parties in the M&A, the importance of effects of national factors and culture in M&A become more transparent.
II. Essay Summary
2. Theoretical Framework
2.1 Definition of Culture
2.2 Cultural Dimensions
2.2.1 Power Distance
2.2.2 Individualism vs. Collectivism
2.2.3 Masculinity vs. Femininity
2.2.4 Uncertainty Avoidance
2.2.5 Long-Term Orientation
3. Cultural Influence on Pre-Merger Performance
3.1 Cultural Due Diligence
3.2 Cultural Compatibility Assessment
3.3 Communication and Integration Challenges
3.4 Leadership and Decision-Making Styles
3.5 Employee Motivation and Engagement
4. Cultural Influence on Post-Merger Performance
4.1 Organizational Culture Alignment
4.2 Change Management Strategies
4.3 Employee Retention and Talent Management
4.4 Knowledge Transfer and Learning
4.5 Performance Measurement and Control Systems
5. Case Studies
5.1 Cross-Border M&A Success Stories
5.2 Cross-Border M&A Failures
5.3 Lessons Learned
6. Conclusion
6.1 Summary of Findings
6.2 Implications for Cross-Border M&A Practitioners
6.3 Recommendations for Future Research

Investment Risk and Return Analysis

Questions
What is the Expected Rate of Return on an investment and what does it tell us about the probability of the risk involved with a particular investment?
In terms of risk, what are the advantages (and/or disadvantages) of a well-diversified portfolio?
Investments are based on the belief that the rate of return justifies or compensates the investor for the risk associated with that particular investment. The risk associated with this investment is associated with the chance that a loss will be incurred. Or, to put it another way, the greater the chance of a loss the riskier the investment. Therefore, some statistical measures of the risk involved with an investment are necessary before the investment is made.

Answers
1. Introduction
The risk and return analysis is a part of the standard investment decision-making process. It is a process in which we compare the expected returns of an investment with the risk associated with it. The general rule for any investor is that the higher the risk of an investment, the higher the expected return. This rule is critical to the decision-making process as the main objective for any investor is to maximize the return on their investment and minimize potential losses. Risk is a measurable possibility of losing or not gaining value. Whereas, return is the reward for taking the risk. Both of them have the same connotation throughout this chapter as in the higher risk or low-risk investment and its effect on the investment’s potential return. Often investors are not concerned with the risk of an investment in its entirety but more the risk of a poor outcome. In this case, the poor outcome would occur when the actual return on an investment is less than what was expected. A poor outcome may have various implications, for example, an individual expecting to finance his retirement with an investment in stocks might consider a poor outcome to be an investment value less than the financing of a comfortable retirement. A main element in the process of risk and return analysis is determining which investment decisions affect the certainty of expected future cash flows. This is because the analysis aims to compare the expected returns with the risk and if there are no changes to the expected returns of an investment then the risk has no impact. This is unlikely to be the case, for example, currency fluctuations and changes in economic conditions can all affect the expected return on an investment. Therefore a decision by the investor to hold onto the investment, invest in it more or take money out of it should be considered as an investment decision that affects the future cash flows and should be included in the analysis. A decision to include it in the analysis may result in the investment in question showing various rates of return and have a different risk. This decision is known as a marginal decision and the analysis of it using the marginal expected return and the marginal rate of time preference is an important aspect of the general risk and return analysis.
1.1 What is the Expected Rate of Return?
The expected rate of return often represents the mean of a distribution of all possible results and is often a probability-weighted calculation influencing the probability that a certain rate of return will happen. This does not have to represent an actual return at all and could be a guess. For example, an investment in the shares of a relatively new and small company with a chance to take a stake in the market of a big industry leader by a takeover of a likely inflated share price could have an expected return, considering the probability of this happening, of say 20% higher than the market, despite only being issued a dividend rate based on the shares.
The expected rate of return is a crucial concept in investment due to the fact that it measures the profitability of an investment or a business. By totaling up the expected earnings from a provided investment over its whole life, then reducing that figure by the original investment, we get the net profit. But in order to determine the profit and the risk of the investment, we need a way of comparing it with other investments of similar magnitude. This is where the expected rate of return is beneficial. By determining the rate of return, we can compare an investment to others to see if it is more or less profitable. And by using the return and risk as a single measure, we can compare to see which is more or less preferable. This is valuable to individuals and businesses, and certainly to financial and investment groups, such as corporate investors and pension funds.
1.2 Understanding the Risk-Return Tradeoff
The concept of risk is intuitively understood. An investor would prefer to receive a higher future payment with certainty than a lower one or one that may or may not eventuate. Probability of distribution of possible future returns is a determinant of the risk involved. Every investment has a possible range of future outcomes to the investor, some more certain than others. A US Treasury bill is regarded as a nearly risk-free investment because the borrowing of current funds by the government issued any no direct value to the bill holder so the bill can be repaid by any future revenue. However, bonds on the other hand are not as certain in terms of a return as stock it is also an uncertain investment. An example would be General Motors buying back many of its bonds prior to maturity and thus avoiding the interest and the principal repayment because of their uncertain financial position in relation to the bond issue. GM may be willing to buy the bond back at a higher price than it issued it for in which case there would be capital gains to the bond holder. So the bond has still uncertain future outcome for GM and the bond holder.
Investment can be broken down into financial and real investment. Using the tuition fee example, it is a real investment as it is an outlay that is expected to produce future benefits (a higher paying job). Financial investment on the other hand is the purchase of a financial asset e.g. a stock or share with the expectations of future income which will be spent on consumption. Whether you are buying stocks or paying tuition fees both can be considered taking a risk as there is always the chance of receiving all or some of the money paid back in the future. Foregone earnings on an investment have the same value as the income that could have been obtained from the job or unemployment requires no spending of the earnings so it is effectively saving the amount of the job and not earning any more than that amount.
An investment is the current commitment of dollars for a period of time in order to derive future payments that will compensate the investor for: (1) the time the funds are committed to the investment and (2) bearing uncertainty about the future size of those payments. There are two types of investment. You are considered to be an investor if you put aside £20 of your weekly income. Your £20 can be looked upon as capital to be invested in a financial or a real asset. However, not all capital expenditure will be considered an investment from an economic perspective. An economics student paying tuition fees can be effectively thought of as investing in themselves but the payment is not included in investment.
2. Risk Measures in Investment Analysis
2.1 Standard Deviation as a Risk Indicator
2.2 Beta Coefficient and Systematic Risk
2.3 Sharpe Ratio and Risk-Adjusted Return
3. Evaluating Investment Risk
3.1 Advantages of a Well-Diversified Portfolio
3.1.1 Spreading Risk Across Different Assets
3.1.2 Reducing Unsystematic Risk
3.1.3 Potential for Stable Returns
3.2 Disadvantages of a Well-Diversified Portfolio
3.2.1 Lower Potential for High Returns
3.2.2 Limited Exposure to Individual Asset Performance
3.2.3 Potential for Lower Market Timing Opportunities
4. Quantifying Risk in Investments
4.1 Risk-Adjusted Return Measures
4.1.1 Treynor Ratio and Portfolio Performance
4.1.2 Jensen’s Alpha and Manager’s Skill
4.1.3 Information Ratio and Active Management
4.2 Value at Risk (VaR) and Downside Risk Analysis
4.2.1 Estimating Potential Losses
4.2.2 Assessing Tail Risk
4.2.3 Portfolio Optimization and Risk Control
5. Conclusion

Learning Theories and Principles for Advanced Practice Nurses

Question
Which learning theories and principles do you think are most useful to the advanced practice nurse (APN) in providing high quality health care to clients, and why?
Submission Instructions:
Your initial post should be at least 500 words, formatted and cited in current APA style with support from at least 2 academic sources.  Your initial post is worth 8 points.

Answer
1. Introduction
The aim of this book is to trace the history of and examine the effectiveness of specific theories and principles for learning. As the first step in our research, a review of the literature on teaching and learning was conducted to understand the full scope of APN’s role as an educator. Much of the research on teaching and learning in advanced practice has been conducted on medical residents and physicians, so we have included literature from the medical field when the education context is pertinent. A small portion of the literature reviewed was found to be specific to advanced practice nursing education, and even less specifically related to nurse practitioner education. Therefore, some literature pertaining to undergraduate nursing and APN relevant clinical teaching was included as principles of learning are often transferable to different educational audiences. Kahn and Nauta state that often times health care providers must act as educators to bring about changes in patient behavior and clinical outcomes. As such, it is important for APNs to not only understand how adults learn but to have a thorough understanding of the teaching-learning process and be competent in specific educational strategies if they are to bring about changes in patient outcomes. This increasing focus on nurse practitioner-led patient education and sustained behavior change led us to include educational literature of learning theories and teaching strategies. Finally, we wanted to learn from the medical education community and other health professions about what has been effective in teaching and learning to apply similar strategies for educators in advanced practice nursing. This information was then used to narrow the scope of our study to select theories and principles that have the most impact and are most applicable to nurse practitioner education. Steps in theory development and testing have been integrated in the examination of specific theories.
1.1 Importance of Learning Theories and Principles for APNs
Learning theories can provide strategies to manage information and critically appraise which resources will be beneficial to their own learning and ultimately improve patient care. Finally, in understanding learning theory, the APN can enhance their own educational role. With the growth of nursing graduate programs, an increasing number of APNs are now in the position to educate future nurses. Knowledge of learning theories, curriculum design, and teaching strategies are critical to this role and fundamental if the educator is to develop competent practitioners who will improve patient care.
Knowledge of learning theory will provide scaffolding to assess individual patients’ learning needs, create an environment that is conducive to learning, build patient motivation, and implement effective teaching strategies. In addition to patient education, learning theory can guide the APN in their own learning. With the rapid expansion of new medical knowledge and virtual explosion of information resources, it is becoming increasingly important for APNs to be lifelong learners.
Knowledge and understanding of learning theories are critical for the APN as it provides the foundation for the strategies and techniques that can be employed to facilitate learning. With diagnoses being more complex, care delivery more diverse, and patient education a common practice, it is imperative that APNs have the skills to enable patients to learn and change behaviors in the healthcare setting.
Descriptive theories describe learning, teaching, and development and are the most concrete of the three. Therefore, they are easier to test through assessment. Prescriptive theories provide strategies or interventions to bring about change in a prescribed direction and have a good chance of being tested. Explanatory theories are so complex that it is uncertain as to whether or not they can be tested (B. Young, 1998).
Learning is an experience of obtaining new knowledge or developing existing knowledge, skills, and abilities and is vital to advanced practice nursing (APN) educational paradigms. Various learning theories attempt to explain this complex phenomenon. There are numerous classifications of learning theories. However, for the purpose of this discussion, the focus will be on three main types: descriptive, prescriptive, and explanatory.
1.2 Purpose of the Study
This research was designed to provide a framework for applying educational theory to an educational program for advanced practice nurses (APNs). Administration of health care is changing dramatically as a result of shifts in demography and policy. This climate requires development of innovative educational programs designed to prepare APNs for new roles in delivering health care to the public. In the last several decades, education has moved from the idea that teaching is simply content delivery to an understanding that learners need to be active participants in the learning process (Knowles, 1980; Eraut, 2000). This change has led to the development of a number of theories to guide the design of learning environments and activities. However, many educators are not familiar with these theories and have difficulty translating them into practice. At the same time, there has been an explosion in research and theory development in the field of nursing education, much of which parallels educational theory outside the discipline. Yet, much of this knowledge has not been consolidated or organized into a framework that is useful for curriculum development. Learning theories and principles are the building blocks for models of effective instruction. We propose that a better understanding of learning theories and principles can help educators develop an innovative curriculum to prepare APNs for complex health care roles in today’s society.
2. Behaviorism
2.1 Classical Conditioning
2.2 Operant Conditioning
2.3 Observational Learning
3. Cognitive Theory
3.1 Information Processing
3.2 Schema Theory
3.3 Problem-Based Learning
4. Social Learning Theory
4.1 Vicarious Learning
4.2 Self-Efficacy
4.3 Modeling
5. Constructivism
5.1 Experiential Learning
5.2 Inquiry-Based Learning
5.3 Collaborative Learning
6. Humanistic Theory
6.1 Maslow’s Hierarchy of Needs
6.2 Person-Centered Care
6.3 Motivation and Self-Determination
7. Adult Learning Theory
7.1 Andragogy
7.2 Self-Directed Learning
7.3 Transformative Learning
8. Application of Learning Theories in APN Practice
8.1 Enhancing Patient Education
8.2 Improving Clinical Decision-Making
8.3 Promoting Evidence-Based Practice

Management and Governance: Ownership and Control, Board Structure and Firm’s Interactions with the Markets PNC Bank

QUESTION
Management and Governance: Ownership and control, board structure and firm’s interactions with the markets PNC BANK
ANSWER
1. Ownership and Control
PNC is a public company and its shareholders have the right to vote on many major decisions affecting the firm. Under the PNC Investor Profile on Yahoo Finance, it is indicated that shareholders have the right to vote on major decisions such as mergers and acquisitions, election of directors, and changes to the company’s charter. With the recent acquisition of National City Corporation, this will be an important time for PNC to maintain shareholder approval for any future decisions. As the right to vote is useless unless it affects an outcome, absolute voting rights are the best situation for the effective use of ownership as a control mechanism. In the case of dual-class stock, the class of stock with superior voting rights has better control than cash flow rights in the same number of shares. This is relevant to PNC as the recent acquisition of National City Corporation has resulted in PNC having issued non-cumulative perpetual preferred shares series B with a liquidation value of $3.7 billion, which carries a higher vote entitlement than common shares. Changes to the company’s charter may dilute voting value and shareholders may protect themselves against this by buying and selling different classes of shares. Measures such as these to protect voting rights are important and PNC shareholders have the right and freedom to hold shares in and to effectively use power to influence the company’s decisions. However, at times, voting rights may also have adverse outcomes for shareholders, so it is important that shareholders have the freedom to sell shares.
The efficiency of stock ownership as a monitoring and control mechanism depends critically on the rights of shareholders to key decisions. McNulty (1966) defines corporate control as the power to influence or make decisions on the allocation of resources by a firm. Shareholder rights, which refer to the right to vote, the right to sell shares, and the right to protect shares against dilution, are an important mechanism in any public company for transferring control from one owner to another and an essential prerequisite for the effective use of ownership as a control mechanism.
1.1. Shareholder Rights
Management rights are the right to access information about the company and to sue the company for a breach of fiduciary duty. The effectiveness of shareholders’ rights in the US can be seen through the court case Smith v Van Gorkom. In this case, the Board of Directors of Trans Union Corporation agreed to a deal to sell the company at $55 per share. In the process, they only discussed the price with the buyer and not other possible buyers. The deal was seen to have breached the Board’s duty of care, and all the directors were sued. This case showed the importance of management rights as the decision by the directors resulted in huge financial losses for the shareholders.
Shareholder rights refer to the powers of the shareholders to make decisions in the company. The decision-making involves voting on certain issues such as the appointment of new Board of Directors, amendments of the corporation’s articles and bylaws, or the decision to merge or sell the corporation. Shareholders’ rights can be divided into two categories: voting rights and management rights. Voting rights give shareholders the right to vote on certain issues, and it is a very important form of participation for shareholders in the decision-making process.
1.2. Voting Rights
Voting rights are the essence of control in the company. There are several different types of shares with different voting rights attached to each type. The most common form of share is known as common stock, differing from non-voting common stock, preferred stock, or dual-class shares. Downtown and Bethem found that the percentage of total votes held by the largest inside blockholder is, on average, 84.9%. While remaining shares are split fairly widely amongst different investors. Inside blockholder being defined as owning at least 5% of company stock. This highlights the immense ownership concentration in the US, as firms tend to concentrate voting rights into the hands of a few key individuals, despite widespread share ownership. Dual-class shares occur when a company issues two different classes of common stock with different voting rights. Bertrand and Mullainathan note that this is common when management is afraid of losing control of decision-making due to investor pressure on particular issues. One such example is Ford Motor Company when, in 2002, it issued a second class of stock with the intention of preserving family control and protecting against the potential threat of a takeover bid. Although this practice is illegal in the UK and most European countries, they found that in the US, dual-class shares are more commonly seen among firms that are in their early growth stages. This suggests that management feels that it is a way of raising finance capital while reducing shareholder interference in company affairs.
1.3. Ownership Concentration
Section “1.3. Ownership Concentration” is the starting point to understand how corporations develop their governance mechanisms. A firm controlled by a single shareholder or a small tightly-knit group of shareholders will have different needs than a corporation with widely dispersed shareholdings. It helps explain the context of governance mechanisms and their needs. If one can understand “who controls the corporation and to what extent,” it will be easier to understand the governance strategy that has been chosen. Shareholders might have been informed about current conditions. PNC already talked about ownership of stockholders that reached 63% shares of the company. Public investors are relieved because they no longer need to inject capital to buy stocks since they feel PNC has had good performance during this time. Shares owned by the public are a short-term program to get some benefits before making long-term investments in the hope that it can be profitable at a certain level. But this is still considering the various possibilities because many retail investors who start to understand the positive performance of PNC have expectations that stocks can still be reached and still have a good price, so they decide to keep the obligations to ensure stocks in the company. While retail investors and other public investors who are planning to buy stocks at this time until the stock price is relatively higher will be affected by the decision to put a premium on consumer direct services and lower the credit. At this time, they still need more time to change the decision because it is still speculation of the company’s stock movements. Now public investors are the most common and have a fairly high influence on the capital, so it must be considered by the company. If considering the role of large institutions, they have different interests. Individually, they are also concerned with policies that provide more benefits because they are indirectly affected and have an interest to repurchase stock at a low level because it consumes a relatively small premium. It is written in this article that about 30% of high-income retail customers are investors who have stock in the company PNC Wealth Management. An affluent investor will respond to a change in the stock price because it will continue to provide advice to other clients, and the level of decision-making will be more stable because it has a relatively small level of risk. High-income PNC customers are still concerned about the credit facilities and cheap loans. Their decision is to sell stock and look back into the movement of stock and interest rates provided. If the decision from stock to find credit facilities is not commensurate with favorable stock bonds, they are very likely to redeem and switch to the purchase of bonds issued by the company. At least changing the trend of holders still expects good stock performance and sees the various decisions still taken by PNC. So there will be much consideration taken by the customer stock or potential new stock buyers to ensure the stock’s performance truly deserves long-term investment. If the decision is still considered effective, PNC can be a good choice to translate stock performance into a debt or financing from another loan. At this stage, stockholders or even a customer can decide to buy stock at a relatively cheap price for a loan will bring a higher level if the company’s performance always brings promise. So, in the various provisions of underlying PNC, it should provide various statements and choices to keep its stock and future investors or new customer stock is still a good choice step in long-term investment. A different story is owned by a public investor. They have an obligation to match capital purchases with quality investments. A long-term investment would be a good choice to still be positive and is also an option to repurchase. It still offers a variety of possibilities for PNC to keep participants, and the expected results can be found in the first paragraph of this article.
1.4. Corporate Governance Mechanisms
Corporate governance refers to the mechanism by which a company is directed and controlled. Boards of directors are responsible for the governance of the company. The shareholders’ role in governance is to appoint the directors and auditors and to satisfy themselves that the board is acting in the best interest of the shareholders and the company. The governance mechanism serves to ensure that the Board is effectively monitoring or managing the top executive. It is particularly important for the owners to make sure that the board has strong monitoring incentives because often the board will consist of the CEO and his cronies. In this case, it is unlikely that the board will act to monitor the CEO who selected them. Ownership & Control PNC exhibits a diffuse ownership characteristic. This can be defined by the fact that no outside investor owns more than 10% of the total shares outstanding. This is particularly important to note in regards to corporate governance at PNC. The level of ownership concentration, in a way, determines the level of monitoring needed. High ownership concentration can often be viewed as a negative as it indicates the CEO might face heavy monitoring and therefore might have less leeway in his decision making. The bank’s decision to include a ‘Lead Director’ is an admission that PNC’s corporate governance failed in the past and a sign that they are concentrating on making sure they don’t make the same mistakes. In the aftermath of the accounting scandal, with one person simultaneously holding the CEO and Chairman position, there is a clear consensus that stronger governance is required and that the board of directors needs to take a more active role in monitoring PNC’s CEO. An internal chief compliance officer and more efficient direct reporting methods to the board are also seen as conscious efforts by PNC to ensure that future errors are quickly identified and do not persist without the board’s knowledge. Although while not specifically related to corporate governance at PNC, the adherence to signing ‘Corporate Integrity Agreements’ issued by the government also illustrates PNC’s desire to move past previous transgressions and towards a more positive public image.
2. Board Structure
2.1. Board Composition
2.2. Board Independence
2.3. Board Diversity
2.4. Board Committees
2.5. Executive Compensation
3. Firm’s Interactions with the Markets
3.1. Regulatory Compliance
3.2. Financial Reporting and Transparency
3.3. Investor Relations
3.4. Market Competition
3.5. Stakeholder Engagement
4. Strategic Decision Making
4.1. Long-Term Planning
4.2. Risk Assessment and Management
4.3. Capital Allocation
4.4. Mergers and Acquisitions
5. Performance Evaluation and Accountability
5.1. Key Performance Indicators
5.2. Financial Performance Analysis
5.3. Internal Control Systems
5.4. External Auditing
5.5. Shareholder Activism
6. Ethical and Legal Considerations
6.1. Code of Conduct and Ethics
6.2. Compliance with Laws and Regulations
6.3. Corporate Social Responsibility
6.4. Legal Risk Management

Muscular Strength Endurance and Flexibility: Assessing and Improving Overall Health and Fitness

Question
Define Muscular strength and give an example of this concept.
Define Muscular endurance and give an example of this activity.
Define Flexibility and name three types of stretching.
In the video, muscular strength, endurance, and flexibility are used to assess how well the ____________________ functions.
How can you improve your overall health and fitness in each of these areas?

Answer
Muscular Strength, Endurance, and Flexibility: Assessing and Improving Overall Health and Fitness
1. Definition and Example of Muscular Strength
The term muscular strength refers to the amount of force a muscle or group of muscles can generate. Muscles differ in strength. Some are strong and can exert a great amount of force using short movements over a brief period of time; these are called power muscles. An example of this would be the muscles of the arm and shoulder which are used when playing a smash in badminton. Other muscles are weaker and can only exert a small force using long movements, or using a small force over a long period of time; these are called endurance muscles. An example of this would be the muscles of the legs when running. There is an almost direct link between bone and muscle strength, i.e. the stronger the muscles the stronger the forces that can be applied to bones and the greater the load they can bear. An example of this is again the muscles of the legs. As well as the advantage of being able to perform everyday tasks more easily, it is also important to have good muscular strength in order to prevent injury. For example, a person who participates in manual handling tasks will be more likely to suffer from back problems if they don’t have good muscle strength in the muscles of the back and abdominal.
1.1. Definition of Muscular Strength
Muscular strength is the capacity of the muscles to apply force to lift weight or carry heavy objects (Fleck and Kraemer, 1987). It is the maximal force a muscle or muscle group can generate. Although the usage of the term force is useful in mathematics and physics, you will notice that in some literature the term strength and force is used interchangeably. For example, when a person speaks about increasing their muscular strength, they are actually referring to increasing the force a particular muscle or muscle group can generate. Using the term force can be confusing, so we will refer to maximal force as muscular strength throughout this subject. Given the conditions in the definition, it is plain that strength is not an all or none quality and will depend on the muscle group being tested, and so the demonstrations of strength will vary.
1.2. Example of Muscular Strength
A good example of muscular strength would be where an individual begins a resistance training program with a health or fitness professional, and progresses to lifting 150 pounds against resistance in a leg press exercise for 8 to 12 repetitions. The same individual could then progress to lifting 230 pounds against resistance for one repetition. This is a good example that demonstrates that the individual has improved the muscular strength in the specific muscle groups involved in the leg press exercise. The increase in the amount of weight being lifted shows an improvement in the strength of the muscles involved. The more the muscles are worked to lift the heavier weight, the more strength is developed. Muscular strength is the ability of the muscles to lift a heavy weight or exert a force against a resistance. A press of greater than body weight shows higher than average leg strength. This individual could then change the type of resistance machine to one that involves a different set of leg muscles and has a different seat angle and pushing direction. If the amount of weight lifted is increased over time, then this would be more evidence of improvement in muscular strength. This is an advantage if the individual had a work or sports requirement to improve strength of these particular muscle groups, or improve overall leg strength. This is because a change or increase in the amount of resistance being pushed, pulled or lifted is one of the major factors that affects strength improvement in specific muscle groups. This case of strength improvement in fitness would best be done using isotonic exercises.
2. Definition and Example of Muscular Endurance
2.1. Definition of Muscular Endurance
2.2. Example of Muscular Endurance
3. Definition of Flexibility
3.1. Definition of Flexibility
4. Types of Stretching
4.1. Static Stretching
4.2. Dynamic Stretching
4.3. Proprioceptive Neuromuscular Facilitation (PNF) Stretching
5. Assessing the Functionality of Muscular Strength, Endurance, and Flexibility
5.1. Importance of Muscular Strength, Endurance, and Flexibility Assessment
5.2. How Muscular Strength, Endurance, and Flexibility Affect Functionality
6. Improving Muscular Strength for Overall Health and Fitness
6.1. Importance of Muscular Strength
6.2. Resistance Training for Muscular Strength Improvement
6.3. Incorporating Compound Exercises for Muscular Strength
7. Enhancing Muscular Endurance for Overall Health and Fitness
7.1. Importance of Muscular Endurance
7.2. Endurance Training Methods
7.3. Circuit Training for Muscular Endurance
8. Enhancing Flexibility for Overall Health and Fitness
8.1. Importance of Flexibility
8.2. Stretching Exercises for Flexibility Improvement
8.3. Incorporating Yoga or Pilates for Flexibility
9. Strategies for Improving Overall Health and Fitness in Muscular Strength, Endurance, and Flexibility
9.1. Setting Goals and Creating a Plan
9.2. Balancing Strength, Endurance, and Flexibility Training
9.3. Proper Nutrition and Rest for Optimal Results

Neurologic Disorders

Question
What is neurologic disorder
Answer
1. Introduction
Neurologic disorders are diseases of the brain, spinal cord, and the nerves that connect them. This includes a large number of conditions which range from those that resolve quickly without treatment to others which are lifelong and need careful management. These conditions are generally due to a reduction in brain function. This means that the brain works less well, or in some cases, more slowly. Of these problems with brain function, some are very specific to the cause and the part of the brain affected, and the impact on a person can vary immensely depending upon the severity of the condition. A useful way to understand brain function is to think of the brain as a complex computer, with malfunctions resulting in software or hardware problems. This leads to error messages, poor function, or failure of certain operations. Neurologic conditions can be very difficult to understand without first acquiring knowledge about the nervous system. It is important to remember that these conditions are real and are not due to anything imagined by the sufferer. They can be very distressing, and every effort should be made to understand a person with a neurologic problem, regardless of what the specific condition may be. Understanding the condition can sometimes be difficult and frustrating, for both sufferers and those close to them, particularly if the condition is hard to diagnose or if there are few treatments available. In such cases, people may find it helpful to contact associations relating to the specific condition or speak to a specialist in neurology.
1.1 Definition of Neurologic Disorders
Neurologic diseases are a prime threat toward a natural time. It is a not unusual place and vast time period and despite the fact that the conquering of infectious illnesses, malnutrition, and maternity deaths has improved, the prevention of neurologic diseases is all the more large due to the fact these troubles growth as human beings live longer. Neurologic problems are sicknesses of the mind, backbone, and the nerves that join them. There are extra than 600 sicknesses of the fearful gadget, along with: – illnesses which includes multiple sclerosis, Parkinson’s sickness, and motor neurone sickness which can be because of the lack of nerve or mind feature – illnesses which includes epilepsy and cerebral palsy wherein the number one trouble is a malfunction of the nervous gadget – sicknesses which includes meningitis or head injury. The scope of neurologic exercise is wide, with many specialities involved. sufferers are regularly complicated and disabled, and treatment can be long term. Generally, neurologic sickness is chronic and progressive, and it affects emotional, bodily, and social function. The primary cause of prevention is to reduce the prevalence of neurologic sickness contained in the community. Voluntary measures can provide safety against precise sickness, along with the vaccination against polio, measles, meningitis, and certain forms of encephalitis. Global prevention of neurologic sickness may be most effectively accomplished with the aid of measures that promote trendy fitness. Some diseases of the frightened tool are related to poverty and malnutrition. Improved understanding in nutrients and the elimination of food poverty, together with improved sanitation, will reduce the incidence of neurologic diseases. A considerable quantity of neurologic diseases is resulting from harmful environmental agents. A better understanding of the nervous system and its function has led to advancements in occupational safety and the prevention of risks in work and sport.
1.2 Causes of Neurologic Disorders
3) Metabolic – Neurologic function is highly dependent upon the metabolic integrity of nervous tissue, and metabolic derangements may have wide-ranging effects.
2) Genetic and Congenital – Disorders which are the result of genetic abnormalities may be inherited or may involve a new mutation. Such abnormalities can affect any aspect of nervous system development or function, and thus the phenotypic manifestations of genetic neurologic disorders are highly variable. Genetic neurologic disorders are beyond the scope of this discussion. Congenital anomalies may result in neurological dysfunction throughout life or may only affect the individual at a certain stage of development. An example of the latter is congenital rubella syndrome, which is due to infection with the rubella virus during embryonic development.
1) Infection – Infection can lead to neurologic dysfunction in several different ways. The infection may primarily involve the nervous system or may be a condition in which the pathogen is widely distributed throughout the body. An example of the former is viral encephalitis, which can be caused by several different viruses. Certain bacteria can produce toxins which have a predilection for nervous tissue. An example of this is the spirochetal bacteria, which causes neurosyphilis. Parasitic infection with organisms such as toxoplasma and cysticercosis can affect the nervous system in several different ways. The organisms may produce focal lesions within the brain or spinal cord. Migrants of foreign tissue in the form of larvae or adult parasites may elicit inflammation as the body attempts to destroy the foreign tissue. More diffuse parasitic infections can result in neurologic dysfunction through a hypersensitivity response, as in the case of eosinophilic meningitis caused by angiostrongylus cantonensis.
Causes can be divided into the following that lead to neurologic disorder:
1.3 Common Types of Neurologic Disorders
Cerebrovascular Diseases: Disorders such as stroke, transient ischemic attack, carotid stenosis, aneurysms, and vascular malformations can cause a variety of neurologic symptoms and signs. The effects of the cerebrovascular disease depend upon the severity and location of the lesion. Often, such diseases cause an acute onset of neurologic deficit, such as paralysis or confusion. A small lesion, such as one that might be seen with a silent stroke, might cause only a very subtle deficit or no deficit at all. In either case, the deficit or its effects may be transient, as seen with transient ischemic attacks, or permanent.
Seizure Disorders: The epilepsies are a spectrum of brain disorders ranging from severe, life-threatening and disabling, to those that are much more benign. In epilepsy, the normal pattern of neuronal activity becomes disturbed, causing strange sensations, emotions, and behavior or sometimes convulsions, muscle spasms, and loss of consciousness. Causes of epilepsy include stroke, brain tumor, trauma, infection, and abnormal brain development. In about 70% of cases, the cause is unknown.
The effects of neurologic disease are as varied as the types of neural tissue and range from simple confusion and mild memory loss to seizures and sudden changes in behavior. The following are some common types of neurologic disorders.
2. Symptoms and Diagnosis
2.1 Recognizing Symptoms of Neurologic Disorders
2.2 Diagnostic Tests for Neurologic Disorders
2.3 Importance of Early Diagnosis
2.4 Understanding Prognosis
3. Treatment Options
3.1 Medications for Neurologic Disorders
3.2 Therapies and Rehabilitation
3.3 Surgical Interventions
3.4 Alternative and Complementary Treatments
4. Living with a Neurologic Disorder
4.1 Coping Strategies and Support Systems
4.2 Lifestyle Modifications
4.3 Managing Emotional and Mental Well-being